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Anti-CEA Antibody (2A576)
Catalog No. TMAB-04199 Copy Product Info
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Anti-CEA Antibody (2A576) is a Mouse antibody targeting CEA. Anti-CEA Antibody (2A576) can be used in IHC-P,IHC-Fr,IF,ELISA.
Anti-CEA Antibody (2A576)
Copy Product Info🥰Excellent
Catalog No. TMAB-04199
Anti-CEA Antibody (2A576) is a Mouse antibody targeting CEA. Anti-CEA Antibody (2A576) can be used in IHC-P,IHC-Fr,IF,ELISA.
Anti-CEA Antibody
(2A576)
(2A576)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-CEA Antibody (2A576) is a Mouse antibody targeting CEA. Anti-CEA Antibody (2A576) can be used in IHC-P,IHC-Fr,IF,ELISA. |
| Ig Type | IgG |
| Clone | 2A576 |
| Reactivity | Human |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (liver cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CEA (B5)) Polyclonal Antibody, Unconjugated (TMAB-04199) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cell membrane; Lipid-anchor, GPI-anchor |
| Tissue Specificity | Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M PBS (pH7.4) with 0.02% Proclin300. |
| Concentration | 1mg/ml |
| Research Background | CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. |
| Immunogen | KLH conjugated synthetic peptide: human CEA/CD66e/CEACAM5 |
| Antigen Species | Human |
| Gene Name | CEACAM5 |
| Gene ID | |
| Protein Name | Carcinoembryonic antigen-related cell adhesion molecule 6 |
| Uniprot ID | |
| Function | Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. |
| Molecular Weight | Theoretical: 150-200 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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