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Anti-CEA Antibody (1V650) (ready to use)

Catalog No. TMAB-04201 Copy Product Info
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Anti-CEA Antibody (1V650) is a Mouse antibody targeting CEA. Anti-CEA Antibody (1V650) can be used in IHC-P,IHC-Fr,ICC/IF,IF.

Anti-CEA Antibody (1V650) (ready to use)

Copy Product Info
🥰Excellent
Catalog No. TMAB-04201

Anti-CEA Antibody (1V650) is a Mouse antibody targeting CEA. Anti-CEA Antibody (1V650) can be used in IHC-P,IHC-Fr,ICC/IF,IF.

Anti-CEA Antibody
(1V650)
(ready to use)
Pack SizePriceUSA StockGlobal StockQuantity
3 mL$847-10 days7-10 days
6 mL$1647-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CEA Antibody (1V650) is a Mouse antibody targeting CEA. Anti-CEA Antibody (1V650) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG2b
Clone
1V650
Reactivity
Human
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded (human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CEA) Monoclonal Antibody, Unconjugated (TMAB-04201) overnight at 4°C, followed by operating according to SP Kit (Mouse) instructions and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded (human gastric carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CEA) Monoclonal Antibody, Unconjugated (TMAB-04201) overnight at 4°C, followed by operating according to SP Kit (Mouse) instructions and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded (human pancreatic cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CEA) Monoclonal Antibody, Unconjugated (TMAB-04201) overnight at 4°C, followed by operating according to SP Kit (Mouse) instructions and DAB staining.
Application
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCell membrane; Lipid-anchor, GPI-anchor
Tissue SpecificityFound in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300.
Research BackgroundCEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
Antigen Details
Immunogen
Human Carcino Embryonic Antigen
Antigen Species
Human
Gene Name
CEACAM5
Gene ID
Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 6
Uniprot ID
Function
Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
Chemical Properties
Molecular WeightTheoretical: 71 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze.
TransportShipping with blue ice.

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