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Anti-CEA Antibody (1V650) is a Mouse antibody targeting CEA. Anti-CEA Antibody (1V650) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 3 mL | $84 | 7-10 days | 7-10 days | |
| 6 mL | $164 | 7-10 days | 7-10 days |
| Description | Anti-CEA Antibody (1V650) is a Mouse antibody targeting CEA. Anti-CEA Antibody (1V650) can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG2b |
| Clone | 1V650 |
| Reactivity | Human |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cell membrane; Lipid-anchor, GPI-anchor |
| Tissue Specificity | Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300. |
| Research Background | CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. |
| Immunogen | Human Carcino Embryonic Antigen |
| Antigen Species | Human |
| Gene Name | CEACAM5 |
| Gene ID | |
| Protein Name | Carcinoembryonic antigen-related cell adhesion molecule 6 |
| Uniprot ID | |
| Function | Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. |
| Molecular Weight | Theoretical: 71 kDa. |
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
| Transport | Shipping with blue ice. |
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