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Anti-CDON Antibody (8I241) (Synonyms: ORCAM, Ihog, HPE11, CDON1, CDO)

Catalog No. TMAY-02169 Copy Product Info
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Anti-CDON Antibody (8I241) is a Rabbit antibody targeting CDON. Anti-CDON Antibody (8I241) can be used in ELISA.

Anti-CDON Antibody (8I241)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02169
Synonyms ORCAM, Ihog, HPE11, CDON1, CDO

Anti-CDON Antibody (8I241) is a Rabbit antibody targeting CDON. Anti-CDON Antibody (8I241) can be used in ELISA.

Anti-CDON Antibody
(8I241)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CDON Antibody (8I241) is a Rabbit antibody targeting CDON. Anti-CDON Antibody (8I241) can be used in ELISA.
SynonymsORCAM, Ihog, HPE11, CDON1, CDO
Ig Type
Rabbit IgG
Clone
8I241
Reactivity
Human
Specificity
Human CDO
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CDON (rh CDON; TMPY-02029; AAI14436.1; Met1-Asp963).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCell adhesion molecule-related, down-regulated by oncogenes (CDON), also known as CDO, is an Ig superfamily member, is a component of a cell surface receptor that positively regulates skeletal myogenesis. Brother of CDO (BOC) is a cell surface receptor that derives its name from the structurally related protein, CDON. They are components of a cell surface receptor that positively regulates myogenesis in vitro. Expression of Cdo and Boc in myoblast cell lines is downregulated by the ras oncogene, and forced re-expression of either Cdo or Boc can override ras-induced inhibition of myogenic differentiation. CDO and BOC play a role in the inverse relationship between differentiation and transformation of cells in the skeletal muscle lineage. CDON binds to Bnip-2 and JLP, scaffold proteins for Cdc42 and p38alpha/beta MAPK, respectively. The Bnip-2/Cdc42 and JLP/p38alpha/beta complexes associate in a CDON-dependent manner, resulting in Bnip-2/Cdc42-dependent p38alpha/beta activation and stimulation of cell differentiation. It is proposed that CDO mediates, at least in part, the effects of cell-cell interactions between muscle precursors that are critical in myogenesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CDON protein (TMPY-02029)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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