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Anti-CDK4 Monoclonal Antibody (1R128)
(Synonyms: PSK-J3, CMM3) Copy Product Info
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Synonyms: PSK-J3, CMM3
Catalog No. TMAT-0478 Copy Product Info
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Anti-CDK4 Monoclonal Antibody (1R128) is a Mouse antibody targeting CDK4. Anti-CDK4 Monoclonal Antibody (1R128) can be used in IHC,IF,FCM.
Anti-CDK4 Monoclonal Antibody
(1R128)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CDK4 Monoclonal Antibody (1R128) is a Mouse antibody targeting CDK4. Anti-CDK4 Monoclonal Antibody (1R128) can be used in IHC,IF,FCM. |
| Synonyms | PSK-J3, CMM3 |
| Ig Type | IgG1 |
| Clone | 1R128 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CDK4 (AA: 77-303) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CDK4 |
| Gene ID | |
| Protein Name | Cyclin-dependent kinase 4 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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