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Anti-CD86 Antibody (6O139)

😃Good
Catalog No. TMAY-03703
Alias LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2

Anti-CD86 Antibody (6O139) is a Mouse antibody targeting CD86. Anti-CD86 Antibody (6O139) can be used in ELISA(Cap).

Anti-CD86 Antibody (6O139)

Anti-CD86 Antibody (6O139)

😃Good
Catalog No. TMAY-03703Alias LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2
Anti-CD86 Antibody (6O139) is a Mouse antibody targeting CD86. Anti-CD86 Antibody (6O139) can be used in ELISA(Cap).
Pack SizePriceAvailabilityQuantity
20 μL$70 7-10 days
100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CD86 Antibody (6O139) is a Mouse antibody targeting CD86. Anti-CD86 Antibody (6O139) can be used in ELISA(Cap).
AliasLAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2
Ig Type
Monoclonal Mouse IgG1
Clone
6O139
Reactivity
Rat
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD86 / B7-2 (rR CD86 / B7-2; TMPY-02016; NP_064466.1; Met1-Ile250). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Rat CD86 / B7-2 Protein (TMPY-02016)
Antigen Species
Rat
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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