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Anti-CD86 Antibody (5K324)

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Catalog No. TMAY-01084
Alias LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2

Anti-CD86 Antibody (5K324) is a Rabbit antibody targeting CD86. Anti-CD86 Antibody (5K324) can be used in ELISA(Cap),ICC/IF.

Anti-CD86 Antibody (5K324)

Anti-CD86 Antibody (5K324)

😃Good
Catalog No. TMAY-01084Alias LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2
Anti-CD86 Antibody (5K324) is a Rabbit antibody targeting CD86. Anti-CD86 Antibody (5K324) can be used in ELISA(Cap),ICC/IF.
Pack SizePriceAvailabilityQuantity
20 μL$93 7-10 days
100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CD86 Antibody (5K324) is a Rabbit antibody targeting CD86. Anti-CD86 Antibody (5K324) can be used in ELISA(Cap),ICC/IF.
AliasLAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2
Ig Type
Monoclonal Rabbit IgG
Clone
5K324
Reactivity
Human
Verified Activity
Immunofluorescence staining of B7-2 in Raji cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-human B7-2 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green).
Application
ELISA(Cap),ICC/IF
Recommended Dose
ICC-IF: 1:20-1:100; ELISA(Cap): 1:250-1:2000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CD86 / B7-2 (rh CD86 / B7-2; TMPY-01180; NP_008820.2; Met1-His239).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human CD86 / B7-2 Protein (TMPY-01180)
Antigen Species
Human
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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