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Anti-CD86 Antibody (5K324)
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Catalog No. TMAY-01084
Alias LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2
Anti-CD86 Antibody (5K324) is a Rabbit antibody targeting CD86. Anti-CD86 Antibody (5K324) can be used in ELISA(Cap),ICC/IF.
Anti-CD86 Antibody (5K324)
Anti-CD86 Antibody (5K324)
😃Good
Catalog No. TMAY-01084Alias LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2
Anti-CD86 Antibody (5K324) is a Rabbit antibody targeting CD86. Anti-CD86 Antibody (5K324) can be used in ELISA(Cap),ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 20 μL | $93 | 7-10 days | 7-10 days | |
| 100 μL | $270 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD86 Antibody (5K324) is a Rabbit antibody targeting CD86. Anti-CD86 Antibody (5K324) can be used in ELISA(Cap),ICC/IF. |
| Synonyms | LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2 |
| Ig Type | Rabbit IgG |
| Clone | 5K324 |
| Reactivity | Human |
| Specificity | Human B7-2/CD86 |
| Verified Activity | Immunofluorescence staining of B7-2 in Raji cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-human B7-2 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). |
| Application | |
| Recommended Dose | ICC-IF: 1:20-1:100; ELISA(Cap): 1:250-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD86 / B7-2 (rh CD86 / B7-2; TMPY-01180; NP_008820.2; Met1-His239). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CD86 / B7-2 Protein (TMPY-01180) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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