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Anti-CD86 Antibody (5K324) (Synonyms: LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2)

Name: Anti-CD86 Antibody (5K324)
Brand: TargetMol
SKU: TMAY-01084
Rating: 4.5 (1 reviews)

Catalog No. TMAY-01084 Copy Product Info

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Anti-CD86 Antibody (5K324) is a Rabbit antibody targeting CD86. Anti-CD86 Antibody (5K324) can be used in ELISA(Cap),ICC/IF.

Anti-CD86 Antibody (5K324)

Copy Product Info

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Catalog No. TMAY-01084

Synonyms LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2

Anti-CD86 Antibody (5K324) is a Rabbit antibody targeting CD86. Anti-CD86 Antibody (5K324) can be used in ELISA(Cap),ICC/IF.

Anti-CD86 Antibody
(5K324)

Pack Size	Price	USA Stock	Global Stock	Quantity
20 μL	$93	7-10 days	7-10 days
100 μL	$270	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-CD86 Antibody (5K324) is a Rabbit antibody targeting CD86. Anti-CD86 Antibody (5K324) can be used in ELISA(Cap),ICC/IF.
Synonyms	LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2
Ig Type	Rabbit IgG
Clone	5K324
Reactivity	Human
Specificity	Human B7-2/CD86
Verified Activity	Immunofluorescence staining of B7-2 in Raji cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-human B7-2 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green).
Application	ELISA(Cap) ICC/IF
Recommended Dose	ICC-IF: 1:20-1:100; ELISA(Cap): 1:250-1:2000
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Human CD86 / B7-2 (rh CD86 / B7-2; TMPY-01180; NP_008820.2; Met1-His239).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human CD86 / B7-2 Protein (TMPY-01180)
Antigen Species	Human
Biology Area	Cancer Drug Targets

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

LAB-72LAB 72B-70B 70

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