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Anti-CD83 Antibody (4E53)

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Catalog No. TMAY-03409
Alias CD83 molecule

Anti-CD83 Antibody (4E53) is a Rabbit antibody targeting CD83. Anti-CD83 Antibody (4E53) can be used in FCM.

Anti-CD83 Antibody (4E53)

Anti-CD83 Antibody (4E53)

😃Good
Catalog No. TMAY-03409Alias CD83 molecule
Anti-CD83 Antibody (4E53) is a Rabbit antibody targeting CD83. Anti-CD83 Antibody (4E53) can be used in FCM.
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100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Monoclonal

Application: FCM

Reactivity: Mouse
AliasCD83 molecule
Ig Type
Rabbit IgG
Clone
4E53
Reactivity
Mouse
Verified Activity
Flow cytometric analysis of Mouse CD83 expression on LPS-stimulated BABL/c splenocytes. Cells were stained with purified anti-Mouse CD83, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD83 (rM CD83; TMPY-02156; O88324; Met1-Arg133).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhance the rate of tumor growth and inhibit the T cell growth.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Mouse CD83 Protein (TMPY-02156)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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