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Anti-CD83 Antibody (1G44)

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Catalog No. TMAY-02047
Alias CD83 molecule

Anti-CD83 Antibody (1G44) is a Mouse antibody targeting CD83. Anti-CD83 Antibody (1G44) can be used in FCM.

Anti-CD83 Antibody (1G44)

Anti-CD83 Antibody (1G44)

😃Good
Catalog No. TMAY-02047Alias CD83 molecule
Anti-CD83 Antibody (1G44) is a Mouse antibody targeting CD83. Anti-CD83 Antibody (1G44) can be used in FCM.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Mouse Monoclonal

Application: FCM

Reactivity: Human
AliasCD83 molecule
Ig Type
Mouse IgG2b
Clone
1G44
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human CD83 expression on DC. Cells were stained with purified anti-Human CD83, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD83 (rh CD83; TMPY-01829; Q01151-1; Met1-Ala143). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhance the rate of tumor growth and inhibit the T cell growth.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
FITC/PE
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Protein: Human CD83 Protein (TMPY-01829)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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