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Anti-CD69 Antibody (5L858)
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Catalog No. TMAY-01706
Alias VEA, CD69 molecule, AIM, AI452015, 5830438K24Rik
Anti-CD69 Antibody (5L858) is a Rabbit antibody targeting CD69. Anti-CD69 Antibody (5L858) can be used in ELISA(Cap).
Anti-CD69 Antibody (5L858)
Anti-CD69 Antibody (5L858)
😃Good
Catalog No. TMAY-01706Alias VEA, CD69 molecule, AIM, AI452015, 5830438K24Rik
Anti-CD69 Antibody (5L858) is a Rabbit antibody targeting CD69. Anti-CD69 Antibody (5L858) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $93 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA(Cap) Reactivity: Human |
| Alias | VEA, CD69 molecule, AIM, AI452015, 5830438K24Rik |
| Ig Type | Rabbit IgG |
| Clone | 5L858 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD69 / CLEC2C (rh CD69 / CLEC2C; TMPY-01234; NP_001772.1; Ser62-Lys199). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Early activation antigen CD69, also known as activation inducer molecule (AIM), is a single-pass type II membrane protein. Recently, cDNA clones encoding human and mouse CD69 were isolated and showed CD69 to be a member of the C-type lectin superfamily. It is one of the earliest cell surface antigens expressed by T cells following activation. Once expressed, CD69 acts as a costimulatory molecule for T cell activation and proliferation. In addition to mature T cells, CD69 is inducibly expressed by immature thymocytes, B cells, natural killer (NK) cells, monocytes, neutrophils and eosinophils, and is constitutively expressed by mature thymocytes and platelets. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. The structure, chromosomal localization, expression and function of CD69 suggest that it is likely a pleiotropic immune regulator , potentially important in the activation and differentiation of a wide variety of hematopoietic cells. This membrane molecule transiently expresses on activated lymphocytes, and its selective expression in inflammatory infiltrates suggests that it plays a role in the pathogenesis of inflammatory diseases. CD69 plays a crucial role in the pathogenesis of allergen-induced eosinophilic airway inflammation and hyperresponsiveness and that CD69 could be a possible therapeutic target for asthmatic patients. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CD69 / CLEC2C Protein (TMPY-01234) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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