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Anti-CD63 Antibody (2H342)
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Catalog No. TMAB-04044
Anti-CD63 Antibody (2H342) is a Mouse antibody targeting CD63. Anti-CD63 Antibody (2H342) can be used in IHC-P,IHC-Fr,IF,ELISA.
Anti-CD63 Antibody (2H342)
Anti-CD63 Antibody (2H342)
Copy Product Info😃Good
Catalog No. TMAB-04044
Anti-CD63 Antibody (2H342) is a Mouse antibody targeting CD63. Anti-CD63 Antibody (2H342) can be used in IHC-P,IHC-Fr,IF,ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-CD63 Antibody (2H342) is a Mouse antibody targeting CD63. Anti-CD63 Antibody (2H342) can be used in IHC-P,IHC-Fr,IF,ELISA. |
| Ig Type | IgG |
| Clone | 2H342 |
| Reactivity | Human |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded Human Lung Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD63 Monoclonal Antibody, Unconjugated (TMAB-04044) at 1: 100 overnight at 4°C, followed by conjugation to the HRP and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Human melanoma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD63 Monoclonal Antibody, Unconjugated (TMAB-04044) at 1: 100 overnight at 4°C, followed by conjugation to the HRP and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD63 Monoclonal Antibody, Unconjugated (TMAB-04044) at 1: 100 overnight at 4°C, followed by conjugation to the HRP and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Human Tonsil; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD63 Monoclonal Antibody, Unconjugated (TMAB-04044) at 1: 100 overnight at 4°C, followed by conjugation to the HRP and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Human Skeletal muscle; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD63 Monoclonal Antibody, Unconjugated (TMAB-04044) at 1: 100 overnight at 4°C, followed by conjugation to the HRP and DAB staining. 6. Paraformaldehyde-fixed, paraffin embedded Human Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD63 Monoclonal Antibody, Unconjugated (TMAB-04044) at 1: 100 overnight at 4°C, followed by conjugation to the HRP and DAB staining. 7. Paraformaldehyde-fixed, paraffin embedded Human Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CD63 Monoclonal Antibody, Unconjugated (TMAB-04044) at 1:200 overnight at 4°C. Followed by conjugated Goat Anti-Mouse IgG antibody (green, BF488), DAPI (blue) was used to stain the cell nuclei. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Note=Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules. |
| Tissue Specificity | Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012] |
| Immunogen | Recombinant Protein: human CD63 protein |
| Antigen Species | Human |
| Gene Name | CD63 |
| Gene ID | |
| Protein Name | CD63 antigen |
| Uniprot ID | |
| Function | This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation. |
| Molecular Weight | Theoretical: 26 kDa. Actual: 30-50 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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