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Anti-CD33 Monoclonal Antibody (8V589)
(Synonyms: SIGLEC-3, SIGLEC3, p67) Copy Product Info
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Synonyms: SIGLEC-3, SIGLEC3, p67
Catalog No. TMAT-0380 Copy Product Info
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Anti-CD33 Monoclonal Antibody (8V589) is a Mouse antibody targeting CD33. Anti-CD33 Monoclonal Antibody (8V589) can be used in WB,IHC,FCM.
Anti-CD33 Monoclonal Antibody
(8V589)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CD33 Monoclonal Antibody (8V589) is a Mouse antibody targeting CD33. Anti-CD33 Monoclonal Antibody (8V589) can be used in WB,IHC,FCM. |
| Synonyms | SIGLEC-3, SIGLEC3, p67 |
| Ig Type | IgG1 |
| Clone | 8V589 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD) |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD33 (AA: 15-237) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CD33 |
| Gene ID | |
| Protein Name | Myeloid cell surface antigen CD33 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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