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Anti-CD319 Monoclonal Antibody (6W566)
(Synonyms: SLAMF7, CS1, CRACC, 19A) Copy Product Info
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Synonyms: SLAMF7, CS1, CRACC, 19A
Catalog No. TMAT-0373 Copy Product Info
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Anti-CD319 Monoclonal Antibody (6W566) is a Mouse antibody targeting CD319. Anti-CD319 Monoclonal Antibody (6W566) can be used in WB,IHC,FCM.
Anti-CD319 Monoclonal Antibody
(6W566)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CD319 Monoclonal Antibody (6W566) is a Mouse antibody targeting CD319. Anti-CD319 Monoclonal Antibody (6W566) can be used in WB,IHC,FCM. |
| Synonyms | SLAMF7, CS1, CRACC, 19A |
| Ig Type | IgG1 |
| Clone | 6W566 |
| Reactivity | Human,Mouse,Rat,Monkey,Rabbit |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/100-1/500; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (PubMed:11698418). Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K (PubMed:16339536). In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells (By similarity). May play a role in lymphocyte adhesion (PubMed:11802771). In LPS-activated monocytes negatively regulates production of proinflammatory cytokines (PubMed:23695528). |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD319 (AA: extra(23-226)) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | SLAMF7 |
| Gene ID | |
| Protein Name | SLAM family member 7 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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