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Anti-CD314 Monoclonal Antibody (2G841)
(Synonyms: NKG2-D, NKG2D, KLRK1, KLR, D12S2489E) Copy Product Info
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Synonyms: NKG2-D, NKG2D, KLRK1, KLR, D12S2489E
Catalog No. TMAT-0370 Copy Product Info
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Anti-CD314 Monoclonal Antibody (2G841) is a Mouse antibody targeting CD314. Anti-CD314 Monoclonal Antibody (2G841) can be used in WB,FCM.
Anti-CD314 Monoclonal Antibody
(2G841)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CD314 Monoclonal Antibody (2G841) is a Mouse antibody targeting CD314. Anti-CD314 Monoclonal Antibody (2G841) can be used in WB,FCM. |
| Synonyms | NKG2-D, NKG2D, KLRK1, KLR, D12S2489E |
| Ig Type | IgG2a |
| Clone | 2G841 |
| Reactivity | Human, Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD314 (AA: extra 73-216) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | KLRK1 |
| Gene ID | |
| Protein Name | NKG2-D type II integral membrane protein |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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