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Anti-CD283 Monoclonal Antibody (1C980)
(Synonyms: TLR3, IIAE2) Copy Product Info
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Synonyms: TLR3, IIAE2
Catalog No. TMAT-0355 Copy Product Info
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Anti-CD283 Monoclonal Antibody (1C980) is a Mouse antibody targeting CD283. Anti-CD283 Monoclonal Antibody (1C980) can be used in FCM.
Anti-CD283 Monoclonal Antibody
(1C980)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-CD283 Monoclonal Antibody (1C980) is a Mouse antibody targeting CD283. Anti-CD283 Monoclonal Antibody (1C980) can be used in FCM. |
| Synonyms | TLR3, IIAE2 |
| Ig Type | IgG1 |
| Clone | 1C980 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 2008] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD283 (AA: 24-217) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TLR3 |
| Gene ID | |
| Protein Name | Toll-like receptor 3 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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