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Anti-CD28 Antibody (3V776) (Synonyms: CD28 molecule)

Catalog No. TMAY-01885 Copy Product Info
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Anti-CD28 Antibody (3V776) is a Mouse antibody targeting CD28. Anti-CD28 Antibody (3V776) can be used in ELISA.

Anti-CD28 Antibody (3V776)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01885
Synonyms CD28 molecule

Anti-CD28 Antibody (3V776) is a Mouse antibody targeting CD28. Anti-CD28 Antibody (3V776) can be used in ELISA.

Anti-CD28 Antibody
(3V776)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$687-10 days7-10 days
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD28 Antibody (3V776) is a Mouse antibody targeting CD28. Anti-CD28 Antibody (3V776) can be used in ELISA.
SynonymsCD28 molecule
Ig Type
Mouse IgG1
Clone
3V776
Reactivity
Human
Specificity
Human CD28
No cross-reactivity in ELISA with
Mouse CD28
Human CTLA4Mouse CTLA4
Human B7-1
Human B7-2Mouse B7-2
Human β-NGF
Human cell lysate (293 cell line)
Application
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD28 (rh CD28; P10747-1Met 1-Pro 152). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS with 10% Trehalose, 0.02% Tween 80, pH7.0
Research BackgroundCD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CD28 protein
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules, Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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