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Anti-CD276 Monoclonal Antibody (7I131)
(Synonyms: CD276, B7-H3, B7H3, 4Ig-B7-H3) Copy Product Info
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Synonyms: CD276, B7-H3, B7H3, 4Ig-B7-H3
Catalog No. TMAT-0141 Copy Product Info
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Anti-CD276 Monoclonal Antibody (7I131) is a Mouse antibody targeting CD276. Anti-CD276 Monoclonal Antibody (7I131) can be used in WB,IHC,IF,FCM.
Anti-CD276 Monoclonal Antibody
(7I131)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CD276 Monoclonal Antibody (7I131) is a Mouse antibody targeting CD276. Anti-CD276 Monoclonal Antibody (7I131) can be used in WB,IHC,IF,FCM. |
| Synonyms | CD276, B7-H3, B7H3, 4Ig-B7-H3 |
| Ig Type | IgG1 |
| Clone | 7I131 |
| Reactivity | Human,Mouse,Rat,Rabbit,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/100-1/500; IF: 1/50-1/500; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Costimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD276 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CD276 |
| Gene ID | |
| Protein Name | CD276 antigen |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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