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Anti-CD268 Monoclonal Antibody (4B318)
(Synonyms: TNFRSF13C, prolixin, CVID4, BROMIX, BAFF-R, BAFFR) Copy Product Info
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Synonyms: TNFRSF13C, prolixin, CVID4, BROMIX, BAFF-R, BAFFR
Catalog No. TMAT-0349 Copy Product Info
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Anti-CD268 Monoclonal Antibody (4B318) is a Mouse antibody targeting CD268. Anti-CD268 Monoclonal Antibody (4B318) can be used in WB,FCM.
Anti-CD268 Monoclonal Antibody
(4B318)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-CD268 Monoclonal Antibody (4B318) is a Mouse antibody targeting CD268. Anti-CD268 Monoclonal Antibody (4B318) can be used in WB,FCM. |
| Synonyms | TNFRSF13C, prolixin, CVID4, BROMIX, BAFF-R, BAFFR |
| Ig Type | IgG2b |
| Clone | 4B318 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD268 (AA: extra 1-78) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TNFRSF13C |
| Gene ID | |
| Protein Name | Tumor necrosis factor receptor superfamily member 13C |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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