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Anti-CD243 Monoclonal Antibody (7B686)
(Synonyms: PGY1, P-GP, MDR1, GP170, CLCS, ABCB1, ABC20) Copy Product Info
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Synonyms: PGY1, P-GP, MDR1, GP170, CLCS, ABCB1, ABC20
Catalog No. TMAT-0339 Copy Product Info
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Anti-CD243 Monoclonal Antibody (7B686) is a Mouse antibody targeting CD243. Anti-CD243 Monoclonal Antibody (7B686) can be used in FCM.
Anti-CD243 Monoclonal Antibody
(7B686)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-CD243 Monoclonal Antibody (7B686) is a Mouse antibody targeting CD243. Anti-CD243 Monoclonal Antibody (7B686) can be used in FCM. |
| Synonyms | PGY1, P-GP, MDR1, GP170, CLCS, ABCB1, ABC20 |
| Ig Type | IgG1 |
| Clone | 7B686 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD243 (AA: 1149-1280) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ABCB1 |
| Gene ID | |
| Protein Name | ATP-dependent translocase ABCB1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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