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Anti-CD227 Monoclonal Antibody (2C87)
(Synonyms: PUM, PEMT, PEM, MUC1/ZD, MUC-1/X, MUC-1/SEC, MUC-1, MUC1, MCKD1, MCKD, MCD, MAM6, KL-6, H23AG, EMA, CA15-3, ADMCKD1, ADMCKD) Copy Product Info
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Synonyms: PUM, PEMT, PEM, MUC1/ZD, MUC-1/X, MUC-1/SEC, MUC-1, MUC1, MCKD1, MCKD, MCD, MAM6, KL-6, H23AG, EMA, CA15-3, ADMCKD1, ADMCKD
Catalog No. TMAT-0334 Copy Product Info
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Anti-CD227 Monoclonal Antibody (2C87) is a Mouse antibody targeting CD227. Anti-CD227 Monoclonal Antibody (2C87) can be used in IHC,FCM.
Anti-CD227 Monoclonal Antibody
(2C87)
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Product Introduction
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| Description | Anti-CD227 Monoclonal Antibody (2C87) is a Mouse antibody targeting CD227. Anti-CD227 Monoclonal Antibody (2C87) can be used in IHC,FCM. |
| Synonyms | PUM, PEMT, PEM, MUC1/ZD, MUC-1/X, MUC-1/SEC, MUC-1, MUC1, MCKD1, MCKD, MCD, MAM6, KL-6, H23AG, EMA, CA15-3, ADMCKD1, ADMCKD |
| Ig Type | IgG1 |
| Clone | 2C87 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD227 (AA: extra 66-175) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MUC1 |
| Gene ID | |
| Protein Name | Mucin-1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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