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Synonyms: INSR, HHF5
Anti-CD220 Monoclonal Antibody
(8T718)

| Description | Anti-CD220 Monoclonal Antibody (8T718) is a Mouse antibody targeting CD220. Anti-CD220 Monoclonal Antibody (8T718) can be used in WB,IF,FCM. |
| Synonyms | INSR, HHF5 |
| Ig Type | IgG2a |
| Clone | 8T718 |
| Reactivity | Human, Mouse, Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/50-1/200; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD220 (AA: extra 413-624) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | INSR |
| Gene ID | |
| Protein Name | Insulin receptor |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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