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Anti-CD220 Monoclonal Antibody (8T718)

(Synonyms: INSR, HHF5) Copy Product Info
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Synonyms: INSR, HHF5

Catalog No. TMAT-0330 Copy Product Info
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Anti-CD220 Monoclonal Antibody (8T718) is a Mouse antibody targeting CD220. Anti-CD220 Monoclonal Antibody (8T718) can be used in WB,IF,FCM.

Anti-CD220 Monoclonal Antibody
(8T718)

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Product Introduction

Bioactivity
Description
Anti-CD220 Monoclonal Antibody (8T718) is a Mouse antibody targeting CD220. Anti-CD220 Monoclonal Antibody (8T718) can be used in WB,IF,FCM.
SynonymsINSR, HHF5
Ig Type
IgG2a
Clone
8T718
Reactivity
Human, Mouse, Monkey
Application
Recommended Dose
WB: 1/500-1/2000; IF: 1/50-1/200; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThis gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CD220 (AA: extra 413-624) expressed in E. Coli.
Antigen Species
Human
Gene Name
INSR
Gene ID
Protein Name
Insulin receptor
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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