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Synonyms: EBI1, CMKBR7, CDw197, CCR-7, CCR7, CC-CKR-7, BLR2
Anti-CD197 Monoclonal Antibody
(4K950)

| Description | Anti-CD197 Monoclonal Antibody (4K950) is a Mouse antibody targeting CD197. Anti-CD197 Monoclonal Antibody (4K950) can be used in WB,FCM. |
| Synonyms | EBI1, CMKBR7, CDw197, CCR-7, CCR7, CC-CKR-7, BLR2 |
| Ig Type | IgG1 |
| Clone | 4K950 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD197 (AA: extra mix) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CCR7 |
| Gene ID | |
| Protein Name | C-C chemokine receptor type 7 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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