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Anti-CD186 Monoclonal Antibody (6P381)
(Synonyms: TYMSTR, STRL33, CXCR6, CDw186, BONZO) Copy Product Info
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Synonyms: TYMSTR, STRL33, CXCR6, CDw186, BONZO
Catalog No. TMAT-0303 Copy Product Info
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Anti-CD186 Monoclonal Antibody (6P381) is a Mouse antibody targeting CD186. Anti-CD186 Monoclonal Antibody (6P381) can be used in WB,FCM.
Anti-CD186 Monoclonal Antibody
(6P381)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CD186 Monoclonal Antibody (6P381) is a Mouse antibody targeting CD186. Anti-CD186 Monoclonal Antibody (6P381) can be used in WB,FCM. |
| Synonyms | TYMSTR, STRL33, CXCR6, CDw186, BONZO |
| Ig Type | IgG1 |
| Clone | 6P381 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD186 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CXCR6 |
| Gene ID | |
| Protein Name | C-X-C chemokine receptor type 6 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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