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Anti-CD182 Monoclonal Antibody (5S630)
(Synonyms: IL8RB, IL8RA, IL8R2, CXCR2, CMKAR2, CDw128b) Copy Product Info
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Synonyms: IL8RB, IL8RA, IL8R2, CXCR2, CMKAR2, CDw128b
Catalog No. TMAT-0301 Copy Product Info
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Anti-CD182 Monoclonal Antibody (5S630) is a Mouse antibody targeting CD182. Anti-CD182 Monoclonal Antibody (5S630) can be used in IHC,IF,FCM.
Anti-CD182 Monoclonal Antibody
(5S630)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CD182 Monoclonal Antibody (5S630) is a Mouse antibody targeting CD182. Anti-CD182 Monoclonal Antibody (5S630) can be used in IHC,IF,FCM. |
| Synonyms | IL8RB, IL8RA, IL8R2, CXCR2, CMKAR2, CDw128b |
| Ig Type | IgG1 |
| Clone | 5S630 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/100; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD182 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CXCR2 |
| Gene ID | |
| Protein Name | C-X-C chemokine receptor type 2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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