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Anti-CD158D Monoclonal Antibody (6W258)

(Synonyms: KIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, G9P) Copy Product Info
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Synonyms: KIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, G9P

Catalog No. TMAT-0282 Copy Product Info
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Anti-CD158D Monoclonal Antibody (6W258) is a Mouse antibody targeting CD158D. Anti-CD158D Monoclonal Antibody (6W258) can be used in FCM.

Anti-CD158D Monoclonal Antibody
(6W258)

Pack SizePriceUSA StockGlobal StockQuantity
20 µLInquiry7-10 days7-10 days
50 µLInquiry7-10 days7-10 days
100 µLInquiry7-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD158D Monoclonal Antibody (6W258) is a Mouse antibody targeting CD158D. Anti-CD158D Monoclonal Antibody (6W258) can be used in FCM.
SynonymsKIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, G9P
Ig Type
IgG1
Clone
6W258
Reactivity
Human
Application
Recommended Dose
FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundKiller cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the "framework" loci that is present on all haplotypes. Alternate alleles of this gene are represented on multiple alternate reference loci (ALT_REF_LOCs). Alternative splicing results in multiple transcript variants, some of which may not be annotated on the primary reference assembly.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CD158D (AA: extra 22-120) expressed in E. Coli.
Antigen Species
Human
Gene Name
KIR2DL4
Gene ID
Protein Name
Killer cell immunoglobulin-like receptor 2DL4
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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