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Anti-CD124 Monoclonal Antibody (4Z485)
(Synonyms: IL-4RA, IL4RA, IL4R) Copy Product Info
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Synonyms: IL-4RA, IL4RA, IL4R
Catalog No. TMAT-0260 Copy Product Info
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Anti-CD124 Monoclonal Antibody (4Z485) is a Mouse antibody targeting CD124. Anti-CD124 Monoclonal Antibody (4Z485) can be used in FCM.
Anti-CD124 Monoclonal Antibody
(4Z485)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CD124 Monoclonal Antibody (4Z485) is a Mouse antibody targeting CD124. Anti-CD124 Monoclonal Antibody (4Z485) can be used in FCM. |
| Synonyms | IL-4RA, IL4RA, IL4R |
| Ig Type | IgG2b |
| Clone | 4Z485 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD124 (AA: 26-232) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | IL4R |
| Gene ID | |
| Protein Name | Interleukin-4 receptor subunit alpha |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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