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Anti-CCNE1 Monoclonal Antibody (1J384)
(Synonyms: CCNE) Copy Product Info
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Synonyms: CCNE
Catalog No. TMAT-0231 Copy Product Info
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Anti-CCNE1 Monoclonal Antibody (1J384) is a Mouse antibody targeting CCNE1. Anti-CCNE1 Monoclonal Antibody (1J384) can be used in IHC,FCM.
Anti-CCNE1 Monoclonal Antibody
(1J384)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CCNE1 Monoclonal Antibody (1J384) is a Mouse antibody targeting CCNE1. Anti-CCNE1 Monoclonal Antibody (1J384) can be used in IHC,FCM. |
| Synonyms | CCNE |
| Ig Type | IgG1 |
| Clone | 1J384 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CCNE1 (AA: 307-410) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CCNE1 |
| Gene ID | |
| Protein Name | G1/S-specific cyclin-E1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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