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Anti-CCND1 Monoclonal Antibody (1R674)

(Synonyms: U21B31, PRAD1, D11S287E, BCL1) Copy Product Info
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Synonyms: U21B31, PRAD1, D11S287E, BCL1

Catalog No. TMAT-0228 Copy Product Info
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Anti-CCND1 Monoclonal Antibody (1R674) is a Mouse antibody targeting CCND1. Anti-CCND1 Monoclonal Antibody (1R674) can be used in IHC,IF,FCM.

Anti-CCND1 Monoclonal Antibody
(1R674)

Pack SizePriceUSA StockGlobal StockQuantity
20 µLInquiry7-10 days7-10 days
50 µLInquiry7-10 days7-10 days
100 µLInquiry7-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CCND1 Monoclonal Antibody (1R674) is a Mouse antibody targeting CCND1. Anti-CCND1 Monoclonal Antibody (1R674) can be used in IHC,IF,FCM.
SynonymsU21B31, PRAD1, D11S287E, BCL1
Ig Type
IgG1
Clone
1R674
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; IF: 1/100-1/500; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThe protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CCND1 (AA: 167-295) expressed in E. Coli.
Antigen Species
Human
Gene Name
CCND1
Gene ID
Protein Name
G1/S-specific cyclin-D1
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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