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Anti-Cardiac Troponin I (cTnI) Antibody (5I456) is a Mouse antibody targeting Cardiac Troponin I (cTnI). Anti-Cardiac Troponin I (cTnI) Antibody (5I456) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,059 | 7-10 days | 7-10 days | |
| 100 μL | $354 | 7-10 days | 7-10 days |
| Description | Anti-Cardiac Troponin I (cTnI) Antibody (5I456) is a Mouse antibody targeting Cardiac Troponin I (cTnI). Anti-Cardiac Troponin I (cTnI) Antibody (5I456) can be used in IHC-P,IHC-Fr,IF. |
| Clone | 5I456 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:200-2000; IHC-Fr: 1:200-2000; IF: 1:200-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Troponin I is a cardiac and skeletal muscle protein useful in the laboratory diagnosis of heart attack. Troponin I is a part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. |
| Immunogen | KLH conjugated synthetic peptide: human CTn1 |
| Antigen Species | Human |
| Gene Name | TNNI3 |
| Gene ID | |
| Protein Name | Troponin I, cardiac muscle |
| Uniprot ID | |
| Function | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
| Molecular Weight | Theoretical: 23 kDa. Actual: 34-35 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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