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Anti-CAPN1 Antibody (6P683) is a Mouse antibody targeting CAPN1. Anti-CAPN1 Antibody (6P683) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days |
| Description | Anti-CAPN1 Antibody (6P683) is a Mouse antibody targeting CAPN1. Anti-CAPN1 Antibody (6P683) can be used in WB,IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG1, k |
| Clone | 6P683 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:25-50; IHC-Fr: 1:25-100; IF: 1:100-500; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding. |
| Tissue Specificity | Ubiquitous. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
| Immunogen | KLH conjugated synthetic peptide: human CAPN1 |
| Antigen Species | Human |
| Gene Name | CAPN1 |
| Gene ID | |
| Protein Name | Calpain-1 catalytic subunit |
| Uniprot ID | |
| Function | Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. |
| Molecular Weight | Theoretical: 78 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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