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Anti-CAMK2 beta Antibody (7C496)
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Catalog No. TMAB-03590
Anti-CAMK2 beta Antibody (7C496) is a Mouse antibody targeting CAMK2 beta. Anti-CAMK2 beta Antibody (7C496) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-CAMK2 beta Antibody (7C496)
Anti-CAMK2 beta Antibody (7C496)
😃Good
Catalog No. TMAB-03590
Anti-CAMK2 beta Antibody (7C496) is a Mouse antibody targeting CAMK2 beta. Anti-CAMK2 beta Antibody (7C496) can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CAMK2 beta Antibody (7C496) is a Mouse antibody targeting CAMK2 beta. Anti-CAMK2 beta Antibody (7C496) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG1 |
| Clone | 7C496 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (Probable). |
| Tissue Specificity | Expressed in skeletal muscle. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The multifunctional CaMKII beta, or Ca2+/calmodulin-dependent protein kinase II, is a well known effector of calcium- and calmodulin- mediated functions. It is present in many tissues but is most abundant in the brain. CaMKII is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Autophosphorylation plays an important role in the regulation of the kinase activity. CaMKII is required for synaptic plasticity, as in Long Term Potentiation (LTP), a cellular model for learning and memory. |
| Immunogen | Recombinant Protein: human CAMK2 between 1-503 amino acids |
| Antigen Species | Human |
| Gene Name | CAMK2B |
| Gene ID | |
| Protein Name | Calcium/calmodulin-dependent protein kinase type II subunit beta |
| Uniprot ID | |
| Function | Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplamic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplamic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. |
| Molecular Weight | Theoretical: 61 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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