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Synonyms: MYCC, MRTL, c-Myc, bHLHe39
Anti-C-MYC Monoclonal Antibody
(4E894)

| Description | Anti-C-MYC Monoclonal Antibody (4E894) is a Mouse antibody targeting C-MYC. Anti-C-MYC Monoclonal Antibody (4E894) can be used in IHC,FCM. |
| Synonyms | MYCC, MRTL, c-Myc, bHLHe39 |
| Ig Type | IgG1 |
| Clone | 4E894 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human C-MYC (AA: (290-439)) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MYC |
| Gene ID | |
| Protein Name | Myc proto-oncogene protein |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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