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Anti-C-MYC Monoclonal Antibody (4E894)

(Synonyms: MYCC, MRTL, c-Myc, bHLHe39) Copy Product Info
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Synonyms: MYCC, MRTL, c-Myc, bHLHe39

Catalog No. TMAT-0631 Copy Product Info
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Anti-C-MYC Monoclonal Antibody (4E894) is a Mouse antibody targeting C-MYC. Anti-C-MYC Monoclonal Antibody (4E894) can be used in IHC,FCM.

Anti-C-MYC Monoclonal Antibody
(4E894)

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Product Introduction

Bioactivity
Description
Anti-C-MYC Monoclonal Antibody (4E894) is a Mouse antibody targeting C-MYC. Anti-C-MYC Monoclonal Antibody (4E894) can be used in IHC,FCM.
SynonymsMYCC, MRTL, c-Myc, bHLHe39
Ig Type
IgG1
Clone
4E894
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human C-MYC (AA: (290-439)) expressed in E. Coli.
Antigen Species
Human
Gene Name
MYC
Gene ID
Protein Name
Myc proto-oncogene protein
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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