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Synonyms: SCFR, PBT, KIT, C-Kit, CD117
Anti-C-Kit Monoclonal Antibody
(5T505)

| Description | Anti-C-Kit Monoclonal Antibody (5T505) is a Mouse antibody targeting C-Kit. Anti-C-Kit Monoclonal Antibody (5T505) can be used in IHC. |
| Synonyms | SCFR, PBT, KIT, C-Kit, CD117 |
| Ig Type | IgG1 |
| Clone | 5T505 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | C-kit (CD117, 145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of C-kit expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | KIT |
| Gene ID | |
| Protein Name | Mast/stem cell growth factor receptor Kit |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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