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Anti-C-jun Antibody (2A229)
Catalog No. TMAB-04371 Copy Product Info
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Anti-C-jun Antibody (2A229) is a Mouse antibody targeting C-jun. Anti-C-jun Antibody (2A229) can be used in WB.
Anti-C-jun Antibody (2A229)
Copy Product Info🥰Excellent
Catalog No. TMAB-04371
Anti-C-jun Antibody (2A229) is a Mouse antibody targeting C-jun. Anti-C-jun Antibody (2A229) can be used in WB.
Anti-C-jun Antibody
(2A229)
(2A229)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-C-jun Antibody (2A229) is a Mouse antibody targeting C-jun. Anti-C-jun Antibody (2A229) can be used in WB. |
| Ig Type | IgG |
| Clone | 2A229 |
| Reactivity | Human |
| Verified Activity | Sample: Lane 1: Human 293T cell lysates Lane 2: Recombinant human C-jun protein Primary: Anti-C-jun (TMAB-04371) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 36 kDa Observed band size: 37,62 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun. |
| Immunogen | Recombinant Protein: human C-jun protein |
| Antigen Species | Human |
| Gene Name | JUN |
| Gene ID | |
| Protein Name | Transcription factor AP-1 |
| Uniprot ID | |
| Function | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. |
| Molecular Weight | Theoretical: 36 kDa. Actual: 43/36 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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