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Anti-BTK Monoclonal Antibody (2A335)
(Synonyms: BTK) Copy Product Info
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Synonyms: BTK
Catalog No. TMAT-0183 Copy Product Info
🥰Excellent
Anti-BTK Monoclonal Antibody (2A335) is a Mouse antibody targeting BTK. Anti-BTK Monoclonal Antibody (2A335) can be used in WB,IHC,IF.
Anti-BTK Monoclonal Antibody
(2A335)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-BTK Monoclonal Antibody (2A335) is a Mouse antibody targeting BTK. Anti-BTK Monoclonal Antibody (2A335) can be used in WB,IHC,IF. |
| Synonyms | BTK |
| Ig Type | IgG1 |
| Clone | 2A335 |
| Reactivity | Human,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases.All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini.BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of BTK expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | BTK |
| Gene ID | |
| Protein Name | Tyrosine-protein kinase BTK |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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