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Anti-BRAF Monoclonal Antibody (3B686)
(Synonyms: RAFB1, NS7, B-RAF1, BRAF1, B-raf) Copy Product Info
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Synonyms: RAFB1, NS7, B-RAF1, BRAF1, B-raf
Catalog No. TMAT-0179 Copy Product Info
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Anti-BRAF Monoclonal Antibody (3B686) is a Mouse antibody targeting BRAF. Anti-BRAF Monoclonal Antibody (3B686) can be used in WB,IHC,FCM.
Anti-BRAF Monoclonal Antibody
(3B686)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-BRAF Monoclonal Antibody (3B686) is a Mouse antibody targeting BRAF. Anti-BRAF Monoclonal Antibody (3B686) can be used in WB,IHC,FCM. |
| Synonyms | RAFB1, NS7, B-RAF1, BRAF1, B-raf |
| Ig Type | IgG1 |
| Clone | 3B686 |
| Reactivity | Human, Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human BRAF (AA: 299-447) expressed in HEK293-6e. |
| Antigen Species | Human |
| Gene Name | BRAF |
| Gene ID | |
| Protein Name | Serine/threonine-protein kinase B-raf |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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