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Anti-BAX Monoclonal Antibody (6D313)
(Synonyms: BCL2L4) Copy Product Info
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Synonyms: BCL2L4
Catalog No. TMAT-0147 Copy Product Info
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Anti-BAX Monoclonal Antibody (6D313) is a Mouse antibody targeting BAX. Anti-BAX Monoclonal Antibody (6D313) can be used in WB,IHC,FCM.
Anti-BAX Monoclonal Antibody
(6D313)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-BAX Monoclonal Antibody (6D313) is a Mouse antibody targeting BAX. Anti-BAX Monoclonal Antibody (6D313) can be used in WB,IHC,FCM. |
| Synonyms | BCL2L4 |
| Ig Type | IgG2a |
| Clone | 6D313 |
| Reactivity | Human,Mouse,Rat,Rabbit,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/1000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human BAX (AA: 13-160) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | BAX |
| Gene ID | |
| Protein Name | Apoptosis regulator BAX |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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