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Synonyms: HSPC104, BACE, ASP2
Anti-BACE1 Monoclonal Antibody
(8H347)

| Description | Anti-BACE1 Monoclonal Antibody (8H347) is a Mouse antibody targeting BACE1. Anti-BACE1 Monoclonal Antibody (8H347) can be used in WB,IF,FCM. |
| Synonyms | HSPC104, BACE, ASP2 |
| Ig Type | IgG1 |
| Clone | 8H347 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | BACE1 |
| Gene ID | |
| Protein Name | beta-secretase 1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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