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Anti-BACE1 Monoclonal Antibody (8H347)

(Synonyms: HSPC104, BACE, ASP2) Copy Product Info
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Synonyms: HSPC104, BACE, ASP2

Catalog No. TMAT-0143 Copy Product Info
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Anti-BACE1 Monoclonal Antibody (8H347) is a Mouse antibody targeting BACE1. Anti-BACE1 Monoclonal Antibody (8H347) can be used in WB,IF,FCM.

Anti-BACE1 Monoclonal Antibody
(8H347)

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Product Introduction

Bioactivity
Description
Anti-BACE1 Monoclonal Antibody (8H347) is a Mouse antibody targeting BACE1. Anti-BACE1 Monoclonal Antibody (8H347) can be used in WB,IF,FCM.
SynonymsHSPC104, BACE, ASP2
Ig Type
IgG1
Clone
8H347
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundCerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli.
Antigen Species
Human
Gene Name
BACE1
Gene ID
Protein Name
beta-secretase 1
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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