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Anti-B7-H3 Antibody (7G651) (Synonyms: CD276 molecule, B7RP-2, B7-H3, B7H3, 4Ig-B7-H3)

Catalog No. TMAY-03503 Copy Product Info
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Anti-B7-H3 Antibody (7G651) is a Rabbit antibody targeting B7-H3. Anti-B7-H3 Antibody (7G651) can be used in ELISA.

Anti-B7-H3 Antibody (7G651)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03503
Synonyms CD276 molecule, B7RP-2, B7-H3, B7H3, 4Ig-B7-H3

Anti-B7-H3 Antibody (7G651) is a Rabbit antibody targeting B7-H3. Anti-B7-H3 Antibody (7G651) can be used in ELISA.

Anti-B7-H3 Antibody
(7G651)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2687-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-B7-H3 Antibody (7G651) is a Rabbit antibody targeting B7-H3. Anti-B7-H3 Antibody (7G651) can be used in ELISA.
SynonymsCD276 molecule, B7RP-2, B7-H3, B7H3, 4Ig-B7-H3
Ig Type
Rabbit IgG
Clone
7G651
Reactivity
Mouse
Specificity
Mouse B7-H3
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse B7-H3/CD276 (rM B7-H3/CD276; TMPY-04064; NP_598744.1; Met1-Phe244).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundB7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse B7-H3/CD276 Protein (TMPY-04064)
Antigen Species
Mouse
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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