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Synonyms: TELO1, TEL1, ATE, ATDC, ATD, ATC, ATA, AT1
Anti-ATM Monoclonal Antibody
(7T10)

| Description | Anti-ATM Monoclonal Antibody (7T10) is a Mouse antibody targeting ATM. Anti-ATM Monoclonal Antibody (7T10) can be used in IHC,IF,FCM. |
| Synonyms | TELO1, TEL1, ATE, ATDC, ATD, ATC, ATA, AT1 |
| Ig Type | IgG2b |
| Clone | 7T10 |
| Reactivity | Human, Mouse, Monkey, Rat |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ATM (AA: 2577-3056) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ATM |
| Gene ID | |
| Protein Name | Serine-protein kinase ATM |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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