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Anti-ATM Monoclonal Antibody (7T10)

(Synonyms: TELO1, TEL1, ATE, ATDC, ATD, ATC, ATA, AT1) Copy Product Info
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Synonyms: TELO1, TEL1, ATE, ATDC, ATD, ATC, ATA, AT1

Catalog No. TMAT-0121 Copy Product Info
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Anti-ATM Monoclonal Antibody (7T10) is a Mouse antibody targeting ATM. Anti-ATM Monoclonal Antibody (7T10) can be used in IHC,IF,FCM.

Anti-ATM Monoclonal Antibody
(7T10)

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Product Introduction

Bioactivity
Description
Anti-ATM Monoclonal Antibody (7T10) is a Mouse antibody targeting ATM. Anti-ATM Monoclonal Antibody (7T10) can be used in IHC,IF,FCM.
SynonymsTELO1, TEL1, ATE, ATDC, ATD, ATC, ATA, AT1
Ig Type
IgG2b
Clone
7T10
Reactivity
Human, Mouse, Monkey, Rat
Application
Recommended Dose
IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThe protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human ATM (AA: 2577-3056) expressed in E. Coli.
Antigen Species
Human
Gene Name
ATM
Gene ID
Protein Name
Serine-protein kinase ATM
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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