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Anti-APOE Monoclonal Antibody (2O907)
(Synonyms: MGC1571, LPG, LDLCQ5, AD2) Copy Product Info
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Synonyms: MGC1571, LPG, LDLCQ5, AD2
Catalog No. TMAT-0089 Copy Product Info
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Anti-APOE Monoclonal Antibody (2O907) is a Mouse antibody targeting APOE. Anti-APOE Monoclonal Antibody (2O907) can be used in IHC,FCM.
Anti-APOE Monoclonal Antibody
(2O907)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-APOE Monoclonal Antibody (2O907) is a Mouse antibody targeting APOE. Anti-APOE Monoclonal Antibody (2O907) can be used in IHC,FCM. |
| Synonyms | MGC1571, LPG, LDLCQ5, AD2 |
| Ig Type | IgG1 |
| Clone | 2O907 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Tissue specificity: Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ApoE expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | APOE |
| Gene ID | |
| Protein Name | Apolipoprotein E |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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