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Anti-APAF1 Monoclonal Antibody (8D809)
(Synonyms: CED4, APAF-1) Copy Product Info
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Synonyms: CED4, APAF-1
Catalog No. TMAT-0078 Copy Product Info
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Anti-APAF1 Monoclonal Antibody (8D809) is a Mouse antibody targeting APAF1. Anti-APAF1 Monoclonal Antibody (8D809) can be used in IF,FCM.
Anti-APAF1 Monoclonal Antibody
(8D809)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-APAF1 Monoclonal Antibody (8D809) is a Mouse antibody targeting APAF1. Anti-APAF1 Monoclonal Antibody (8D809) can be used in IF,FCM. |
| Synonyms | CED4, APAF-1 |
| Ig Type | IgG2b |
| Clone | 8D809 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/100-1/500; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human APAF1 (AA: 1138-1237) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | APAF1 |
| Gene ID | |
| Protein Name | Apoptotic protease-activating factor 1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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