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Anti-ALPL Monoclonal Antibody (4S370)

(Synonyms: TNSALP, TNAP, HOPS, AP-TNAP, APTNAP) Copy Product Info
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Synonyms: TNSALP, TNAP, HOPS, AP-TNAP, APTNAP

Catalog No. TMAT-0067 Copy Product Info
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Anti-ALPL Monoclonal Antibody (4S370) is a Mouse antibody targeting ALPL. Anti-ALPL Monoclonal Antibody (4S370) can be used in WB,IHC,FCM.

Anti-ALPL Monoclonal Antibody
(4S370)

Pack SizePriceUSA StockGlobal StockQuantity
20 µLInquiry7-10 days7-10 days
50 µLInquiry7-10 days7-10 days
100 µLInquiry7-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ALPL Monoclonal Antibody (4S370) is a Mouse antibody targeting ALPL. Anti-ALPL Monoclonal Antibody (4S370) can be used in WB,IHC,FCM.
SynonymsTNSALP, TNAP, HOPS, AP-TNAP, APTNAP
Ig Type
IgG1
Clone
4S370
Reactivity
Human,Mouse,Rat,Rabbit
Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThere are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human ALPL expressed in E. Coli.
Antigen Species
Human
Gene Name
ALPL
Gene ID
Protein Name
Alkaline phosphatase, tissue-nonspecific isozyme
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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