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Synonyms: TNSALP, TNAP, HOPS, AP-TNAP, APTNAP
Anti-ALPL Monoclonal Antibody
(4S370)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
| Description | Anti-ALPL Monoclonal Antibody (4S370) is a Mouse antibody targeting ALPL. Anti-ALPL Monoclonal Antibody (4S370) can be used in WB,IHC,FCM. |
| Synonyms | TNSALP, TNAP, HOPS, AP-TNAP, APTNAP |
| Ig Type | IgG1 |
| Clone | 4S370 |
| Reactivity | Human,Mouse,Rat,Rabbit |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ALPL expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ALPL |
| Gene ID | |
| Protein Name | Alkaline phosphatase, tissue-nonspecific isozyme |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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