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Anti-ALDH2 Monoclonal Antibody (7V197)
(Synonyms: ALDM, ALDHI, ALDH-E2) Copy Product Info
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Synonyms: ALDM, ALDHI, ALDH-E2
Catalog No. TMAT-0059 Copy Product Info
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Anti-ALDH2 Monoclonal Antibody (7V197) is a Mouse antibody targeting ALDH2. Anti-ALDH2 Monoclonal Antibody (7V197) can be used in WB,IHC,IF,FCM.
Anti-ALDH2 Monoclonal Antibody
(7V197)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-ALDH2 Monoclonal Antibody (7V197) is a Mouse antibody targeting ALDH2. Anti-ALDH2 Monoclonal Antibody (7V197) can be used in WB,IHC,IF,FCM. |
| Synonyms | ALDM, ALDHI, ALDH-E2 |
| Ig Type | IgG1 |
| Clone | 7V197 |
| Reactivity | Human,Mouse,Rat,Monkey,Rabbit |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/100-1/500; IF: 1/50-1/500; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ALDH2 (AA: 317-517) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ALDH2 |
| Gene ID | |
| Protein Name | Aldehyde dehydrogenase, mitochondrial |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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