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Anti-ADORA2A Monoclonal Antibody (2E990)

(Synonyms: RDC8, ADORA2, A2aR) Copy Product Info
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Synonyms: RDC8, ADORA2, A2aR

Catalog No. TMAT-0032 Copy Product Info
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Anti-ADORA2A Monoclonal Antibody (2E990) is a Mouse antibody targeting ADORA2A. Anti-ADORA2A Monoclonal Antibody (2E990) can be used in WB,IF,FCM.

Anti-ADORA2A Monoclonal Antibody
(2E990)

Pack SizePriceUSA StockGlobal StockQuantity
20 µLInquiry7-10 days7-10 days
50 µLInquiry7-10 days7-10 days
100 µLInquiry7-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ADORA2A Monoclonal Antibody (2E990) is a Mouse antibody targeting ADORA2A. Anti-ADORA2A Monoclonal Antibody (2E990) can be used in WB,IF,FCM.
SynonymsRDC8, ADORA2, A2aR
Ig Type
IgG2a
Clone
2E990
Reactivity
Human,Mouse,Rat,Monkey
Application
Recommended Dose
WB: 1/500-1/1000; IF: 1/100-1/500; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThis gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human ADORA2A (AA: 274-412) expressed in E. Coli.
Antigen Species
Human
Gene Name
ADORA2A
Gene ID
Protein Name
Adenosine receptor A2a
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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