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Anti-ACTH Monoclonal Antibody (6X148)

(Synonyms: POMC, POC, NPP, MSH, LPH, CLIP) Copy Product Info
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Synonyms: POMC, POC, NPP, MSH, LPH, CLIP

Catalog No. TMAT-0021 Copy Product Info
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Anti-ACTH Monoclonal Antibody (6X148) is a Mouse antibody targeting ACTH. Anti-ACTH Monoclonal Antibody (6X148) can be used in IF,FCM.

Anti-ACTH Monoclonal Antibody
(6X148)

Pack SizePriceUSA StockGlobal StockQuantity
20 µLInquiry7-10 days7-10 days
50 µLInquiry7-10 days7-10 days
100 µLInquiry7-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ACTH Monoclonal Antibody (6X148) is a Mouse antibody targeting ACTH. Anti-ACTH Monoclonal Antibody (6X148) can be used in IF,FCM.
SynonymsPOMC, POC, NPP, MSH, LPH, CLIP
Ig Type
IgG1
Clone
6X148
Reactivity
Human
Application
Recommended Dose
IF: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThis gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human ACTH expressed in E. Coli.
Antigen Species
Human
Gene Name
POMC
Gene ID
Protein Name
Pro-opiomelanocortin
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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