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Anti-ABL2 Monoclonal Antibody (6I252)
(Synonyms: FLJ41441, FLJ31718, FLJ22224, ARG, ABLL) Copy Product Info
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Synonyms: FLJ41441, FLJ31718, FLJ22224, ARG, ABLL
Catalog No. TMAT-0011 Copy Product Info
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Anti-ABL2 Monoclonal Antibody (6I252) is a Mouse antibody targeting ABL2. Anti-ABL2 Monoclonal Antibody (6I252) can be used in IF.
Anti-ABL2 Monoclonal Antibody
(6I252)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-ABL2 Monoclonal Antibody (6I252) is a Mouse antibody targeting ABL2. Anti-ABL2 Monoclonal Antibody (6I252) can be used in IF. |
| Synonyms | FLJ41441, FLJ31718, FLJ22224, ARG, ABLL |
| Ig Type | IgG1 |
| Clone | 6I252 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | ABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases. ABL2 and c-Abl share 89%, 90 and 93% identity in their SH3, SH2 and tyrosine domain, but only 29% identity in the carboxy-terminal half. The human c-Abl and ABL2 genes are expressed ubiquitously. ABL2 had been detected predominantly in the cytoplasm, whereas c-Abl shows both cytoplasmic and nuclear localization. c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl. Recently, TEL-ARG fusion transcripts have also been identified in acute myeloid leukemias (AML). The Abl family kinases may also interact with receptor tyrosine signaling pathways and regulate cellular function such as cell cycle progression, gene transcription and organization of the actin cytoskeletons in neurons. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of ABL2 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ABL2 |
| Gene ID | |
| Protein Name | Tyrosine-protein kinase ABL2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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