others — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19936	Xantphos
	Xantphos, a ligand in the coupling reaction of Buchwald, Suzuki and others, is a metal chelating ligand that can be used to catalyze the reaction.
T3365	Rebaudioside C	Dulcoside B	Others , Endogenous Metabolite
	Dulcoside B (Rebaudioside C (Dulcoside B)) is a natural sweeteners used for diabetics and others on carbohydrate-controlled diets.		Others , Endogenous Metabolite
T2006	Omecamtiv mecarbil	CK-1827452	ATPase , Myosin
	Omecamtiv mecarbil (CK-1827452) has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among othe...		ATPase , Myosin
T13572	Cancer-Targeting Compound 1		Others
	Cancer-Targeting Compound 1 can be used in the study of hormone-related cancers, including the treatment or prevention of fibroids, uterine leiomyomas, polycystic ovarian syndrome, or hormone-dependent Cancer, among othe...		Others
T8687	Diaminohydroxypropanetetraacetic acid		Others
	Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others		Others
T3099	Pinometostat	EPZ-5676	Histone Methyltransferase
	Pinometostat (EPZ-5676) has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.		Histone Methyltransferase
T7528	3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-enoate		Others
	3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-enoate is a useful research compound for many research applications, including the fields of chemistry and life sciences, among others.		Others
T2669	Berzosertib	VX-970,VE-822	ATM/ATR
	Berzosertib (VE-822) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.		ATM/ATR
T2503	PAC-1	Procaspase activating compound 1	Apoptosis , Caspase , Autophagy
	PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others.		Apoptosis , Caspase , Autophagy
T3049	TPCA-1	GW683965,IKK2 Inhibitor IV,TPCA1	Apoptosis , IκB/IKK , STAT
	TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases and enzymes.		Apoptosis , IκB/IKK , STAT
TN7029	(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol		Others
	(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol is a useful research compound for many research applications, including the fields of chemistry and life sciences, among others.		Others
T2709	TAK-901	TAK901	JAK , CDK , Src , Aurora Kinase
	TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others.		JAK , CDK , Src , Aurora Kinase
T2365	Pilaralisib	SAR245408,XL-147	PI3K
	Pilaralisib (XL-147) is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K). Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid...		PI3K
T1109	(Z)-Capsaicin	Zucapsaicin,Civamide,cis-Capsaicin	TRP/TRPV Channel , HSV
	(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer of natural capsaicin that has shown therapeutic efficacy in pain ac...		TRP/TRPV Channel , HSV
T8794	4-MMPB	15-Lipoxygenase Inhibitor 1	Apoptosis , Others , Lipoxygenase
	15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxyg...		Apoptosis , Others , Lipoxygenase
T9195	SHR0302	ARQ252	Apoptosis , JAK
	SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2).		Apoptosis , JAK
T6157	Devimistat	CPI-613,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid	Apoptosis , Dehydrogenase , Mitochondrial Metabolism
	Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism. It has potent...		Apoptosis , Dehydrogenase , Mitochondrial Metabolism
T6883	Samotolisib	GTPL8918,LY3023414	DNA-PK , PI3K , mTOR , Autophagy
	Samotolisib (LY3023414) is an oral ATP competitive inhibitor of the class I PI3K isoforms, DNA-PK, and mTOR. Samotolisib (LY3023414) has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, ...		DNA-PK , PI3K , mTOR , Autophagy
T0093L	Sorafenib	Bay 43-9006	Apoptosis , Raf , VEGFR , FLT , Ferroptosis , PDGFR , c-Kit , Autophagy
	Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. Sorafenib has antitumor activity...
T14052	5-IAF	5-Iodoacetamidofluorescein
	5-IAF is a fluorescein derivative of indoleacetamide, a fluorescent probe that can be used to label proteins and others containing free thiols (cysteine side chains). 5-IAF can label the catalytic (alpha) subunit of dog ...