Target / Pathway Focused

A target-focused library is a screening collection of compounds specifically tailored to modulate the function of a particular target or a protein family. These libraries not only reduce waste by eliminating compounds that are unlikely to bind to target proteins, but often lead to the increased potency and specificity of binders, as demonstrated for c-Src kinase. Compared to large and diverse screening libraries, using relatively small and targeted collections significantly improves the odds of finding potential drug candidates, thus further reduces the costs of drug discovery.

Cat No.	product name
L3510	Methylation Compound Library	128 methylation-related compounds that can be used for high-throughput and high-content screening.	128 compounds
L2800	Serotonin Receptor-Targeted Compound Library	A unique collection of 268 compounds targeting serotonin receptors for high throughput screening and high content screening;	268 compounds
L3900	DNA Damage & Repair Compound Library	A unique collection of 910 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);	910 compounds
L8600	Ubiquitination Compound Library	A unique collection of 210 ubiquitination related small chemicals can be used for high throughput and high content screening；	210 compounds
L3800	NF-κB Signaling Compound Library	A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;	729 compounds
L1500	GPCR Compound Library	A unique collection of 1940 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research;	1940 compounds
L1110	Microtubule-Targeted Compound Library	A unique collection of 142 microtubule-targeted compounds can be used in HTS and HCS;	142 compounds
L1120	AMPK-Targeted Compound Library	80 well-chosen unique AMPK-targeted small molecules；	80 compounds
L7400	Sodium Channel Blocker Library	A unique collection of 118 sodium channel blockers and agonists for high throughput and high content screening;	118 compounds
L3300	Histamine & Melatonin Receptor-Targeted Compound Library	A unique collection of 153 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs;	153 compounds
L5300	Mitochondria-Targeted Compound Library	A unique collection of 812 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;	812 compounds
L8100	Cell Cycle Compound Library	A unique collection of 677 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);	677 compounds
L7600	Chemokine Inhibitor Library	A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;	59 compounds
L3600	Cytokine Inhibitor Library	A unique collection of 604 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;	604 compounds
L4100	TGF-beta/Smad Compound Library	A unique collection of 184 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;	184 compounds
L1510	Nuclear Receptor Compound Library	A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;	531 compounds
L3200	Autophagy Compound Library	A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;	1248 compounds
L4300	Wnt/Hedgehog/Notch Compound Library	A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;	237 compounds
L8700	Ferroptosis Compound Library	A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；	779 compounds
L8720	Pyroptosis Compound Library	1066 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.	1066 compounds
L2700	Adrenergic Receptor-Targeted Compound Library	A unique collection of 193 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification;	193 compounds
L9420	Exosome Compound Library	76 exosome-related compounds that can be used for high-throughput and high-content screening.	76 compounds
L4800	Angiogenesis related Compound Library	A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);	1353 compounds
L1610	FDA-Approved Kinase Inhibitor Library	A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.	263 compounds
L7200	Calcium Channel Compound Library	A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;	140 compounds
L9000	Apoptosis Compound Library	A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;	1760 compounds
L8500	HIF-1 Signaling Pathway Compound Library	A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；	1336 compounds
L1200	Epigenetics Compound Library	Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs;	953 compounds
L2610	Neurotransmitter Receptor Compound Library	A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；	1513 compounds
L1300	PI3K-AKT-mTOR Compound Library	A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;	420 compounds
L8710	Cuproptosis Compound Library	TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.	400 compounds
L1100	Protease Inhibitor Library	A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;	343 compounds
L7300	Potassium Channel Blocker Library	A unique collection of 152 potassium channel blockers and agonists for high throughput and high content screening;	152 compounds
L3700	JAK-STAT Compound Library	A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening;	252 compounds
L1400	MAPK Inhibitor Library	A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;	365 compounds
L2200	Tyrosine Kinase Inhibitor Library	A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;	1016 compounds
L1600	Kinase Inhibitor Library	A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;	2720 compounds
L9700	Endoplasmic Reticulum Stress Compound Library	A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);	193 compounds
L1580	GPCR Compound Library Plus	Well-chosen 338 GPCR targeting compounds with unique structures;	338 compounds
L1310	Cytoskeletal Signaling Pathway Compound Library	A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS；	759 compounds
L2000	Inhibitor Library	A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;	8328 compounds
L9100	Phosphatase Inhibitor Library	A collection of 79 phosphatase inhibitors with known activity;	79 compounds
L2300	Ion Channel Inhibitor Library	A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;	931 compounds
L2600	Neuronal Signaling Compound Library	A unique collection of 2540 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;	2540 compounds