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By Target- Caspase
- PKC(1)
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Results for "
tigilanol tiglate
" in TargetMol Product Catalog- Inhibitors & Agonists1
Tigilanol tiglate
EBC-46, EBC46
T28975943001-56-7
Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate promotes mitochondrial/endoplasmic reticulum dysfunction, leading to ATP depletion, caspase activation, and gasdermin E cleavage. It induces immunogenic cell death, enhancing the response to immune checkpoint blockade in both target tumours and non-injected tumours, resulting in tumour regression.
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