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Results for "

nematodes

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    35
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    2
    TargetMol | Peptide_Products
  • Dye Reagents
    1
    TargetMol | Dye_Reagents
  • Natural Products
    9
    TargetMol | Natural_Products
Pyrantel pamoate
Pyrantel embonate
T125922204-24-6
Pyrantel pamoate (Pyrantel embonate) is a depolarizing neuromuscular blocking agent. This compound is commonly used as an anthelmintic to treat parasitic worm infections, effectively paralyzing nematodes by inhibiting their neuromuscular activity.
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Selamectin
UK-124114
T4059220119-17-5
Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, selamectin (0.1 μg ml) shows the effect of growth inhibition.
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Amyl-2-Methylbutyrate
T8404868039-26-9
Amyl-2-Methylbutyrate (Pentyl 2-methylbutanoate) shows nematicidal activity against pine wood nematodes and can be used to study nematicides.
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nerolidol acetate
T92792306-78-7
Nerolidol acetate is a natural sesquiterpene with anti-cancer, anti-inflammatory, antibacterial and anti-insect activities. Nerolidol acetate can inhibit parasite activity and inhibit schistosomiasis, nematodes, malaria, etc. Nerolidol acetate protects cells from oxidative damage to lipids, proteins and DNA, and has a protective effect on mouse hippocampal nerve cells.
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Tioxazafen
T13928330459-31-9
Tioxazafen is a disubstituted oxadiazole, and is a broad-spectrum seed treatment nematicide.
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TargetMol | Inhibitor Sale
UK-124114
UNII-A2669OWX9N, Selamectin
T0124165108-07-6
UK-124114 (Selamectin) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, selamectin (0.1 μg ml) shows the effect of growth inhibition.
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Pyrantel
Strongid, Pyrequan, Pyrantelum, Pirantele, Pin-X
T0395L15686-83-6
Pyrantel is a nicotinic receptor agonist and a depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes.
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2-4 weeks
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Avenacoside B
T12496035920-91-3
Avenacoside B can be extracted from oats and has antinematode activity, which enhances osteogenic activity.
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Haloxon
T15462321-55-1
Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants.
    7-10 days
    Inquiry
    UM-C162
    T2015801799734-10-3
    UM-C162, a benzimidazole derivative, offers protection to nematodes from Staphylococcus aureus infections. It inhibits biofilm formation without impairing bacterial viability. Additionally, UM-C162 disrupts the production of Staphylococcus aureus hemolysins, proteases, and coagulases. This compound holds potential as an antivirulence agent for managing Staphylococcus aureus infections.
    • Inquiry Price
    10-14 weeks
    Size
    QTY
    Fluopimomide
    LH2010A
    T2016881309859-39-9
    Fluopimomide (LH2010A), a powerful insecticide, is extensively utilized in the control of agricultural pests. It adversely affects the growth, locomotor behavior, reproduction, and lifespan of nematodes. Concurrently, it leads to increased production of reactive oxygen species (ROS), accumulation of lipids and lipofuscins, as well as a rise in malondialdehyde content. Additionally, Fluopimomide inhibits the antioxidant system of nematodes.
    • Inquiry Price
    10-14 weeks
    Size
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    Isazofos
    T20180342509-80-8
    Isazofos is a broad-spectrum organophosphate insecticide and nematicide effective in controlling a variety of lawn pests, such as nematodes (Radopholus similis). It also demonstrates efficacy in managing rice gall midge.
    • Inquiry Price
    10-14 weeks
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    AChE-IN-83
    T2056562828439-12-7
    AChE-IN-83 (compound f1) is an AChE inhibitor that suppresses nematode growth and acetylcholinesterase activity in rice seeds while being safe for the seeds. It specifically targets Aphelenchoides besseyi, with an LC50 of 19.0 μg mL over 48 hours. AChE-IN-83 impedes nematode populations and behaviors in rice seeds, damages the nematode cuticle, and induces reactive oxygen species, lipofuscin, and lipid generation within the nematodes.
    • Inquiry Price
    10-14 weeks
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    Antibiofilm agent prodrug 1
    T205727
    Antibiofilm agent prodrug 1 (Compound 5c) demonstrates antibacterial properties by inhibiting biofilm formation and iron uptake. It effectively suppresses Pseudomonas aeruginosa PAO1 with a minimum inhibitory concentration (MIC) of 1.07 μM. In addition, Antibiofilm agent prodrug 1 exhibits anti-infective activity in Caenorhabditis elegans, enhancing the survival rate of the nematodes.
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    Luxabendazole
    HOE 216V
    T2096090509-02-7
    Luxabendazole is a benzimidazole carbamate broad-spectrum anthelmintic agent. It has proved to be effective against immature and adult stages of the major gastrointestinal nematodes, cestodes, and trematodes.
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    CD 1530
    CD-1530, CD1530
    T21686107430-66-0
    CD 1530 is a selective and potent RARγ agonist (Kd:150 nM) with potential anticancer activity, shows insecticidal activity against Cryptobacterium hidradii nematodes, and can be used to study oral carcinogenesis.
    • Inquiry Price
    6-8 weeks
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    ML358
    ML-358,ML 358
    T258201158607-44-3
    ML358 is a selective SKN-1 pathway inhibitor involved in drug detoxification and resistance in nematodes.
    • Inquiry Price
    6-8 weeks
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    Amidantel hydrochloride
    BAY-d 8815,BAY d 8815
    T2997969884-15-7
    Amidantel hydrochloride is a new aminophenylamidine with an interesting anthelminthic spectrum. In rodents the compound is active against nematodes, filariae and cestodes. Of special interest is the high efficacy in dogs against hookworms and large roundw
    • Inquiry Price
    6-8 weeks
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    Amidantel free base
    BAYd 8815,BAY d8815,BAYd-8815,Amidantel,BAY d-8815,BAY d 8815
    T29979L49745-00-8
    Amidantel free base is a new aminophenylamidine with an interesting anthelminthic spectrum. In rodents the compound is active against nematodes, filariae and cestodes. Of special interest is the high efficacy in dogs against hookworms and large roundworms
    • Inquiry Price
    6-8 weeks
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    Doramectin aglycone
    T357331987883-26-0
    Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysis product doramectin monosaccharide . Doramectin undergoes one round of acid-catalyzed hydrolysis to form doramectin monosaccharide which is then hydrolyzed again to remove the remaining saccharide unit and form doramectin aglycone.
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    Doramectin monosaccharide
    T35734165108-44-1
    Doramectin monosaccharide is an acid degradation product of doramectin, a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. Doramectin undergoes acid-catalyzed hydrolysis to form doramectin monosaccharide.
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    Nanchangmycin
    Nanchangmycin A
    T660165101-87-3
    Nanchangmycin (Nanchangmycin A), a polyether antibiotic, is similar to the structure of dianemycin. It is very potent against the broad spectrum of harmful nematodes and insects but not for mammals and plants.
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    Emodepside
    Bay 44-4400
    T7901155030-63-0
    Emodepside (Bay 44-4400) is an anthelmintic drug that is effective against a number of gastrointestinal nematodes,with broad-spectrum anthelmintic activity.
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    TargetMol | Inhibitor Sale
    Fosthiazate
    T8062598886-44-3
    Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes, including Meloidogyne spp., Globodera spp., and Pratylenchus spp., by inhibiting acetylcholinesterase synthesis [1].
    • Inquiry Price
    8-10 weeks
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